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Irina V Lebedeva Selected Research

Polyribonucleotide Nucleotidyltransferase (Polynucleotide Phosphorylase)

5/2008Progression elevated gene-3 promoter (PEG-Prom) confers cancer cell selectivity to human polynucleotide phosphorylase (hPNPase(old-35))-mediated growth suppression.
10/2004Human polynucleotide phosphorylase (hPNPaseold-35): a potential link between aging and inflammation.
7/2003Down-regulation of Myc as a potential target for growth arrest induced by human polynucleotide phosphorylase (hPNPaseold-35) in human melanoma cells.

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Irina V Lebedeva Research Topics

Disease

33Neoplasms (Cancer)
10/2017 - 10/2002
31Melanoma (Melanoma, Malignant)
11/2010 - 01/2002
10Infections
11/2007 - 01/2002
6Pancreatic Neoplasms (Pancreatic Cancer)
09/2008 - 01/2005
4Prostatic Neoplasms (Prostate Cancer)
04/2008 - 11/2003
4Glioma (Gliomas)
02/2008 - 02/2003
4Carcinoma (Carcinomatosis)
02/2007 - 11/2003
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
06/2008 - 02/2007
2Ovarian Neoplasms (Ovarian Cancer)
08/2006 - 08/2004
2Necrosis
08/2003 - 07/2003
2Glioblastoma (Glioblastoma Multiforme)
08/2003 - 07/2003
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2021
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2021
1Alzheimer Disease (Alzheimer's Disease)
01/2021
1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
10/2017
1Colorectal Neoplasms (Colorectal Cancer)
11/2007
1Neoplasm Metastasis (Metastasis)
02/2007
1Lung Neoplasms (Lung Cancer)
02/2007
1Carcinogenesis
01/2005
1Inflammation (Inflammations)
10/2004
1Mitochondrial Diseases (Mitochondrial Disease)
12/2003
1Renal Cell Carcinoma (Grawitz Tumor)
07/2003
1Brain Neoplasms (Brain Tumor)
02/2003

Drug/Important Bio-Agent (IBA)

22InterleukinsIBA
09/2008 - 08/2003
20Proteins (Proteins, Gene)FDA Link
11/2010 - 01/2002
18CytokinesIBA
11/2010 - 02/2003
7Messenger RNA (mRNA)IBA
09/2008 - 01/2002
3Biological ProductsIBA
01/2021 - 10/2002
3Reactive Oxygen Species (Oxygen Radicals)IBA
11/2010 - 12/2003
3Interleukin-10 (Interleukin 10)IBA
06/2008 - 05/2004
3ErbB Receptors (EGF Receptor)IBA
06/2008 - 08/2004
3Polyribonucleotide Nucleotidyltransferase (Polynucleotide Phosphorylase)IBA
05/2008 - 07/2003
3mezereinIBA
09/2006 - 01/2002
3Interferon-betaIBA
09/2006 - 01/2002
2Monoclonal AntibodiesIBA
03/2009 - 11/2007
2perillyl alcoholIBA
09/2008 - 07/2008
2Amino AcidsFDA Link
06/2008 - 08/2006
2Hormones (Hormone)IBA
04/2008 - 11/2003
2CaspasesIBA
04/2008 - 02/2008
2p38 Mitogen-Activated Protein KinasesIBA
08/2006 - 07/2002
2Arsenic Trioxide (Trisenox)FDA Link
01/2005 - 07/2003
2Acetylcysteine (Siran)FDA LinkGeneric
10/2004 - 12/2003
2DNA (Deoxyribonucleic Acid)IBA
08/2003 - 07/2003
2Protein Kinase CIBA
10/2002 - 01/2002
1Protein Isoforms (Isoforms)IBA
10/2017
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
10/2017
1CeramidesIBA
11/2010
1Recombinant ProteinsIBA
06/2008
1Erlotinib Hydrochloride (CP 358,774)FDA Link
06/2008
1bardoxolone methylIBA
04/2008
11- (2- cyano- 3,12- dioxooleana- 1,9- dien- 28- oyl) imidazoleIBA
04/2008
1imidazoleIBA
04/2008
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
04/2008
1Caspase 10IBA
04/2008
1Caspase 9IBA
04/2008
1Caspase 8 (Caspase-8)IBA
04/2008
1bardoxoloneIBA
04/2008
1Caspase 7IBA
04/2008
1Caspase 3 (Caspase-3)IBA
04/2008
1TriterpenesIBA
04/2008
1AcidsIBA
04/2008
1CathepsinsIBA
02/2008
1Pharmaceutical PreparationsIBA
11/2007
1Small Interfering RNA (siRNA)IBA
11/2007
1Singlet OxygenIBA
02/2007
1Antineoplastic Agents (Antineoplastics)IBA
02/2007
1Gefitinib (Iressa)FDA Link
02/2007
1Endoplasmic Reticulum Chaperone BiPIBA
08/2006
1Phosphotransferases (Kinase)IBA
02/2006
1retinamideIBA
01/2005
1Complementary DNA (cDNA)IBA
01/2005
1Chemokine CCL5IBA
10/2004
1Interleukin-6 (Interleukin 6)IBA
10/2004
1Interleukin-8 (Interleukin 8)IBA
10/2004
1NF-kappa B (NF-kB)IBA
10/2004
1NF-KappaB Inhibitor alphaIBA
10/2004
1Matrix Metalloproteinases (MMPs)IBA
10/2004
1Indicators and Reagents (Reagents)IBA
10/2004
1RNA (Ribonucleic Acid)IBA
10/2004
1AgarIBA
08/2004
1Cyclosporine (Ciclosporin)FDA LinkGeneric
12/2003
11,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium SaltIBA
12/2003
1AntioxidantsIBA
12/2003
1Bongkrekic AcidIBA
12/2003
1thiazolyl blueIBA
08/2003
1ExoribonucleasesIBA
07/2003
1adenovirus receptorIBA
07/2003
1Free RadicalsIBA
07/2003
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
04/2003
1SB 203580IBA
07/2002
1HSP27 Heat-Shock ProteinsIBA
07/2002
1interleukin-24 (ST16)IBA
01/2002

Therapy/Procedure

22Therapeutics
03/2009 - 01/2002
8Drug Therapy (Chemotherapy)
03/2009 - 07/2003
4Radiotherapy
03/2009 - 07/2003
2Injections
05/2008 - 09/2006
1Chemoprevention
07/2008
1Molecular Targeted Therapy
02/2006
1Aftercare (After-Treatment)
01/2002